Science and Discovery

Gene Therapy

3 articles

Editorial illustration for Viral vs. Non-Viral Gene Delivery: Why No Single Vector Wins Every Therapy
Life & Biology

Viral vs. Non-Viral Gene Delivery: Why No Single Vector Wins Every Therapy

Gene therapy delivery relies on either viral or non-viral vectors, each with distinct advantages and limitations. The optimal vector choice is a complex, product-specific decision balancing efficacy, safety, durability, and manufacturability.

David Grossman·October 18, 2026
Scientists in a modern lab examining glowing DNA strands, symbolizing the advancements in gene therapy for treating genetic disorders.
Explainers

What Are Advances in Gene Therapy for Genetic Disorders?

By May 2025, the U.S. Food and Drug Administration (FDA) had approved 44 cell and gene therapies, a dramatic increase signaling a new era for treating previously incurable genetic disorders. Imagine t

Marcus Cole·August 16, 2026
Close-up cinematic view of the CRISPR-Cas9 complex precisely editing a DNA double helix, symbolizing advancements in genetic modification and disease treatment.
Explainers

CRISPR-Cas9 vs. Prime Editing: From Genetic Scissors to a Word Processor

This article compares CRISPR-Cas9, a gene-editing tool that cuts DNA, with Prime Editing, a more advanced system that functions like a "search and replace" for genetic code. It explores their mechanisms, applications, and the challenges of off-target effects and delivery.

Marcus Cole·June 5, 2026