Immune System
3 articles
One Platform, Three Goals: How mRNA Technology Is Being Retooled for Cancer and Autoimmune Disease
The mRNA technology behind COVID-19 vaccines is a flexible platform that can be retooled to instruct cells to produce specific proteins. This adaptability allows it to train the immune system to attack pathogens or cancer cells, or to induce tolerance in autoimmune diseases.
Four Pathways: How Gut Microbes Push the Immune System Toward Autoimmunity
Gut microbes can drive autoimmune diseases through four main pathways: molecular mimicry, intestinal barrier disruption, T-cell differentiation modulation, and microbial metabolites. These mechanisms highlight the microbiome's dynamic role in regulating immune tolerance and self-attack.
The Human Microbiome: A Key Regulator of Health and Disease
The human microbiome, a complex ecosystem of microorganisms, is vital for health, performing essential functions like digestion and immune regulation. Imbalances, or dysbiosis, are linked to various diseases, driving research into personalized microbiome-based therapies.